A c c e l e r a t o r  M a s s  S p e c t r o m e t r y
Research Services for Drug Development

 

Scientific Advisory Board

 

Bruce Hammock, Ph.D.

Edmund Capparelli, Pharm. D.

James Harris, Ph.D.

John Vogel, Ph.D.

Luis Ruzo, Ph.D.


Dr. Vogel was, until 2005, a Senior Scientist at the Center for Accelerator Mass Spectrometry at Lawrence Livermore National Laboratories (LLNL).  He is distinguished as the founder and most recognizable proponent of biological Accelerator Mass Spectrometry.  Dr. Vogel has published 100's of scientific papers in the field of AMS including its key foundation papers that described the technical aspects of biological AMS.  As a speaker, he is in high demand and is regularly invited to address key international meetings on topics ranging from AMS machinery to biomedical topics that been advanced from the unique capabilities of AMS.  He maintains an Adjunct Professorship in the Department of Nutrition at University of California , Davis.  Dr. Vogel holds several key patents in AMS technology, including applications in biomedical research.  

Dr. Hammock is a distinguished Professor of Entomology & Cancer Research Center and Director of NIEHS-UCD Superfund Basic Research Program at University of California, Davis. Dr. Hammock’s research efforts have had an exemplary impact on many different areas of biology, agriculture and medicine. He has received numerous academic awards including the prestigious Alexander von Humboldt Award in 1995 for his research contributions to U.S. agriculture and the Burroughs Welcome Toxicology Scholar Award from the Society of Toxicology in 1987. He was elected in 1999 to the National Academy of Sciences, one of the highest honors for scientists in the United States.  He was an original adopter of AMS technology and has published many of  the fundamental papers on applied AMS.

Dr. Harris is a Co-founder and Chief Scientific Officer of Bioavailability Systems (BAS) and the sole inventor of all BAS patents. From 1991 to 1996, Dr. Harris worked for the FDA, Center for Drug Evaluation and Research, ultimately becoming a key member in clinical pharmacology research. During that time he published papers on the elucidation of the metabolism of Taxol™ by CYP 3A and the isolation of the principal Taxol™ metabolite. Dr. Harris earned an MS and a PhD in Toxicology from the University of Rochester School of Medicine and Dentistry in 1989 and 1991 respectively, and a BS in Chemistry from Vanderbilt University in 1987.

Dr. Capparelli, Director, Pediatric Pharmacology Research Unit (PPRU) & International Maternal, Pediatric and Adolescent AIDS Clinical Trials (IMPAACT) Network Pharmacology Laboratory; Clinical Professor, Pediatrics Division of Pharmacology and Drug Discovery School of Medicine, Department of Pediatrics and Skagg's School of Pharmacy & Pharmaceutical Sciences University of California, San Diego, will assist Vitalea in the development of tools for pediatric clinical pharmacology using Accelerator- technology, and particularly in applications in clinical trials of treatments of HIV/AIDS and related infections in pediatrics.  Dr. Capparelli received his PharmD degree from the University of California, San Francisco in 1985 and completed Fellowships at Hartford Hospital, Connecticut in 1987 and the University of California, Irvine in 1988. In 1992, he helped secure NIH support for the UC San Diego Pediatric Pharmacology Laboratory to support the Pediatric AIDS Clinical Trials Group (ACTG) and in 1994 co-founded the National Institute of Childhood Health and Human Development supported UC San Diego-Children's Hospital Pediatric Pharmacology Research Unit (PPRU). He has served in leadership roles in both of these networks including chair of the Pediatric ACTG Pharmacology Committee from 2002 through 2004. Dr. Capparelli continues to co-direct these programs as well as direct clinical pharmacology sections of other multi-center NIH sponsored studies. Dr. Capparelli is board certified in Applied Pharmacology and holds appointments with both the UC San Diego School of Medicine and UC San Francisco School of Pharmacy. He is recognized for his work in applying population pharmacokinetic methods in pediatric populations. Dr. Capparelli has served on several NIH workshop panels, the editorial board for Antimicrobial Agents and Chemotherapy and the Advisory Sub-Committee to the FDA in Clinical Pharmacology, and the World Health Organization expert working group on Pediatric HIV/AIDS. Dr. Capparelli has published more than 50 papers and book chapters. 

Dr. Ruzo is founder and managing director of PTRL West. PTRL West is a full service contract research laboratory located in Hercules, California on the San Francisco Bay. The company was founded in 1987. Its sister company in Germany, PTRL Europe, has been in operation since 1992. PTRL West conducts studies needed to satisfy regulatory requirements in the areas of environmental fate, metabolism, and analysis of agrochemicals, industrial chemicals and pharmaceuticals. Dr. Ruzo provides insight and market penetration into the enviromental/agrochemical testing area for which Vitalea's technology is well suited.

 

 

 
John Vogel